Trypanosoma brucei: immunisation with plasmid DNA encoding invariant surface glycoprotein gene is able to induce partial protection in experimental African trypanosomiasis.

Authors: Atouguia J, De Sousa KP, Lança AS, Monteiro GA, Prazeres DM, Silva MS
Journal: Experimental Parasitology
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Trypanosoma+brucei%3A+Immunisation+with+plasmid+DNA+encoding+invariant+surface+glycoprotein+gene+is+able+to+induce+partial+protection+in+experimental+African+trypanosomiasis.

Trypanosoma brucei is the etiological agent responsible for African trypanosomiasis, an infectious pathology which represents a serious problem of public health and economic losses in Sub-Saharan Africa.
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DNA vaccines: a rational design against parasitic diseases

Authors: Atouguia J, Carvalho JA, Monteiro GA, Prazeres DM, Rodgers J
Journal: Expert review of vaccines
Link: http://www.ncbi.nlm.nih.gov/pubmed/20109028

Parasitic diseases are one of the most devastating causes of morbidity and mortality worldwide. Although immunization against these infections would be an ideal solution, the development of effective vaccines has been hampered by specific challenges posed by parasitic pathogens.
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Trypanosoma brucei: immunisation with plasmid DNA encoding invariant surface glycoprotein gene is able to induce partial protection in experimental African trypanosomiasis.

DNA vaccines: a rational design against parasitic diseases

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