Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy
- Autores: Singh T, Lopez CA, Giuberti C, Dennis ML, Itell HL, Heimsath HJ, Webster HS, Roark HK, Merçon de Vargas PR, Hall A, Corey RG, Swamy GK, Dietze R, Lazear HM, Permar SR
- Ano de Publicação: 2019
- Journal: Plos Neglected Tropical Diseases
- Link: https://www.ncbi.nlm.nih.gov/pubmed/31449521
Zika virus (ZIKV) is a newly-identified infectious cause of congenital disease. Transplacental transfer of maternal IgG to the fetus plays an important role in preventing many neonatal infections. However, antibody transfer may also have negative consequences, such as mediating enhancement of flavivirus infections in early life, or trafficking of virus immune complexes to the fetal […]
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