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Home / Archives for Inês Morais

Synthetic Red Blood Cell-Specific Glycolytic Intermediate 2,3-Diphosphoglycerate (2,3-DPG) Inhibits Plasmodium falciparum Development In Vitro

  • Autores: Inês Morais, Márcia M. Medeiros, Maria Carvalho, Judit Morello, Sara M. Teixeira, Suelma Maciel, Janice Nhantumbo, Ana Balau, Margarida T. G. Rosa, Fatima Nogueira, João Alexandre Rodrigues, Filomena A. Carvalho, Alexandra M. M. Antunes, Ana Paula Arez
  • Ano de Publicação: 2022
  • Journal: Frontiers in Cellular and Infection Microbiology, vol 12, art 840968
  • Link: https://doi.org/10.3389/fcimb.2022.840968

Mechanisms of malaria parasite interaction with its host red blood cell may provide potential targets for new antimalarial approaches. Pyruvate kinase deficiency has been associated with resistance to malaria in both experimental models and population studies.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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