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Home / Archives for Gonçalves L

Strengthening the perception-assessment tools for dengue prevention: a cross-sectional survey in a temperate region (Madeira, Portugal)

  • Autores: Gonçalves L, Nazareth T, Porto G, Seixas G, Silva AC, Sousa CA, Teodósio R
  • Ano de Publicação: 2014
  • Journal: BMC Public Health
  • Link: http://www.biomedcentral.com/1471-2458/14/39

Community participation is mandatory in the prevention of Dengue outbreaks. Taking public views into account is crucial to guide more effective planning and quicker community participation in preventing campaigns. This study aims to assess community perceptions of Madeira population in order to explore their involvement in the A. aegypti’s control and reinforce health-educational planning.
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ROC curve estimation: an overview

  • Autores: de Zea Bermudez P, Gonçalves L, Oliveira MR, Subtil A
  • Ano de Publicação: 2014
  • Journal: REVSTAT – Statistical Journal
  • Link: https://www.ine.pt/revstat/pdf/rs140101.pdf

This work overviews some developments on the estimation of the Receiver Operating Characteristic (ROC) curve. Estimation methods in this area are constantly being developed, adjusted and extended, and it is thus impossible to cover all topics and areas of application in a single paper.
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Probing the aurone scaffold against Plasmodium falciparum: Design, synthesis and antimalarial activity

  • Autores: Carrasco MP, dos Santos DJVA, Gois A, Gonçalves L, Guedes RC, Gut J, Haenscheid T, Machado M, Moreira R, Newton AS, Nogueira F, Rosenthal PJ
  • Ano de Publicação: 2014
  • Journal: European Journal of Medicinal Chemistry
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24813880

A library comprising 44 diversely substituted aurones derivatives was synthesized by straightforward aldol condensation reactions of benzofuranones and the appropriately substituted benzaldehydes. Microwave enhanced synthesis using palladium catalyzed protocols was introduced as a powerful strategy for extending the chemical space around the aurone scaffold.
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Prevalence and seasonal variations of canine dirofilariosis in Portugal

  • Autores: Alho AM, Belo S, Ferreira C, Gonçalves L, Landum M, Madeira LC, Meireles J
  • Ano de Publicação: 2014
  • Journal: Veterinary Parasitology
  • Link: http://www.sciencedirect.com/science/article/pii/S0304401714004671

Dirofilariosis is a severe vector-borne emergent disease that is spreading worldwide and becoming a serious threat to human and veterinary public health. Portugal, a Mediterranean country, has favorable climate conditions for mosquito development and survival. At present, accurate data on the prevalence and epidemiological pattern of dirofilariosis in Portugal is scarce and outdated. To study these trends, a project was developed to assess the current prevalence of Dirofilaria immitis infection in shelter dogs as well as the prevalence of Dirofilaria species present in three coastal regions in central Portugal: Coimbra, Santarém, and Setúbal.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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