Anopheles gambiae and A. stephensi Immune Response during Plasmodium berghei Infection Uncovered by Sialotranscriptomic Analysis

Authors: Couto J, de la Fuente J, Domingos A, Ferrolho J
Publication Year: 2016
Journal: International Trends in Immunity

Malaria is caused by parasites of the genus Plasmodium that are transmitted through the bite of female mosquitoes of the genus Anopheles. Responsible for high mobility and mortality rates around the world, this protozoan disease is most common in the tropical and sub-tropical regions. Herein, using a pure transcriptomic data analysis approach on mosquito salivary […]
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Reduction of Mosquito Survival in Mice Vaccinated with Anopheles stephensi Glucose Transporter

Authors: Antunes S, Couto J, de la Fuente J, Domingos A, Ferrolho J
Publication Year: 2017
Journal: BioMed Research International
Link: https://www.hindawi.com/journals/bmri/2017/3428186/

Despite the fact that recent efforts to control/eradicate malaria have contributed to a significant decrease in the number of cases and deaths, the disease remains a global health challenge. Vaccines based on mosquito salivary gland antigens are a potential approach for reducing vector populations and malaria parasites. The Anopheles AGAP007752 gene encodes for a glucose transporter that […]
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Ferritin 1 silencing effect in Rhipicephalus sanguineus sensu lato (Acari: Ixodidae) during experimental infection with Ehrlichia canis

Authors: André MR, Antunes S, Bechara GH, Couto J, Domingos A, Évora PM, Ferrolho J, Machado RZ, Rosa C, Sanches GS
Publication Year: 2017
Journal: Ticks and Tick-Borne Diseases
Link: https://www.sciencedirect.com/science/article/pii/S1877959X1630190X?via%3Dihub

Rhipicephalus sanguineus sensu lato (s.l.) is a very common ectoparasite of domestic dogs able to transmit several pathogens of human and veterinary importance. Tick infestations and tick-borne diseases (TBDs) remain a serious and persistent problem, due to the lack of efficient control measures. It is therefore vital that novel approaches to control are pursued. Whilst […]
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PCR screening of tick-borne agents in sensitive conservation areas, Southeast Portugal

Authors: Antunes S, Domingos A, Duarte LR, Ferrolho J, Melo P, Milhano N, Santos AS, Santos N, Santos PT, Santos-Silva MM
Publication Year: 2017
Journal: Molecular and Cellular Probes
Link: https://www.sciencedirect.com/science/article/pii/S0890850816301153?via%3Dihub

The Southeast region of Portugal, particularly the Guadiana valley, is currently the reintroduction territory of Lynx pardinus (Iberian lynx), one of the most endangered felids in the world that is only found in the Iberian Peninsula. Over the last century, populations have declined, placing L. pardinus at extremely high risk of extinction in the wild and […]
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Deciphering babesia-vector interactions

Authors: Antunes S, Couto J, Domingos A, Ferrolho J, Rosa C
Publication Year: 2017
Journal: Frontiers in Cellular and Infection Microbiology
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627281/

Understanding host-pathogen-tick interactions remains a vitally important issue that might be better understood by basic research focused on each of the dyad interplays. Pathogens gain access to either the vector or host during tick feeding when ticks are confronted with strong hemostatic, inflammatory and immune responses. A prominent example of this is the Babesia spp.—tick—vertebrate host relationship. Babesia spp. […]
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Anopheles gambiae and A. stephensi Immune Response during Plasmodium berghei Infection Uncovered by Sialotranscriptomic Analysis

Reduction of Mosquito Survival in Mice Vaccinated with Anopheles stephensi Glucose Transporter

Ferritin 1 silencing effect in Rhipicephalus sanguineus sensu lato (Acari: Ixodidae) during experimental infection with Ehrlichia canis

PCR screening of tick-borne agents in sensitive conservation areas, Southeast Portugal

Deciphering babesia-vector interactions

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