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Home / Archives for Diego M.A.Guérin

VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases

  • Autores: Aline Maria Vasconcelos Queiroz, Johny Wysllas de Freitas Oliveira, Cláudia Jassica Moreno, Diego M.A.Guérin, Marcelo Sousa-Silva
  • Ano de Publicação: 2021
  • Journal: Vaccines, 9(3), art 220, [Special Issue: Host Immune Response to Infectious Diseases pp 1 - 9]
  • Link: https://doi.org/10.3390/vaccines9030220

ABSTRACT Research on vaccines against trypanosomatids, a family of protozoa that cause neglected tropical diseases, such as Chagas disease, leishmaniasis, and sleeping sickness, is a current need. Today, according to modern vaccinology, virus-like particle (VLP) technology is involved in many vaccines, including those undergoing studies related to COVID-19. The potential use of VLPs as vaccine […]
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Antibodies response induced by recombinant virus-like particles from Triatoma virus and chimeric antigens from Trypanosoma cruzi

  • Autores: Aline Maria Vasconcelos Queiroz, Yulia Aleksandrovna Yanshina, Emily Thays da Silva Rodrigues, Fred Luciano Neves Santos, Paola Alejandra Fiorani Celedon, Sweta Maheshwari, Sandra Beatriz Gabelli, Carla Stephanie Peucelle Rubio, Aritz Durana, Diego M.A.Guérin, Marcelo Sousa-Silva
  • Link: https://doi.org/10.1016/j.vaccine.2021.05.039

ABSTRACT ‘Background:’ The infection caused by the protozoan Trypanosoma cruzi affects humans and is called as Chagas disease. Currently, the main measures available to reduce the incidence of this disease are drug treatment and vector control. Traditionally, the development of vaccines occurs mainly through the use of antigenic candidates of the etiologic agent in the […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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+351 213 652 600
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