Lesser protein degradation machinery correlates with higher BM86 tick vac- cine efficacy in Rhipicephalus annulatus when compared to Rhipicephalus micro-plus

• Authors: Almazán C, de Mera IGF, del Valle M, Marina A, Mateos-Hernández L, Popara M, Villar M, Domingos A
• Journal: Vaccine
• Link: http://www.ncbi.nlm.nih.gov/pubmed/23973246

Infestations with cattle ticks, Rhipicephalus (Boophilus) microplus and Rhipicephalus annulatus, economically impact cattle production in tropical and subtropical regions of the world. Vaccines containing the recombinant R. microplus BM86 gut antigen were developed and commercialized to induce an immunological protection in cattle against tick infestations. These vaccines demonstrated that tick control by vaccination is cost-effective, reduces environmental contamination and prevents the selection of drug resistant ticks that result from repeated acaricide applications.
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