Leishmania infantum exerts immunomodulation in canine Kupffer cells reverted by meglumine antimoniate
- Authors: Alexandre-Pires G, Alves-Azevedo R, de Jesus J, Ligeiro D, Lopes-Ventura S, Pereira da Fonseca I, Pereira MA, Rafael-Fernandes M, Rodrigues A, Santos M, Santos-Gomes G, Santos-Mateus D, Tomás AM, Valério-Bolas A
- Publication Year: 2017
- Journal: Comparative Immunology Microbiology and Infectious Diseases
- Link: https://www.sciencedirect.com/science/article/pii/S0147957117300863?via%3Dihub
Kupffer cells (KC) are the liver macrophage population that resides in the hepatic sinusoids and efficiently phagocyte pathogens by establishing an intimate contact with circulating blood. KC constitute the liver host cells in Leishmania infection, nevertheless little is described about their role, apart from their notable contribution in granulomatous inflammation. The present study aims to […]
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