Triosephosphate isomerase gene promoter variation:-5G/A and-8G/A polymorphisms in clinical malaria groups in two African populations

• Authors: Arez AP, Fernandes N, Guerra M, Machado P, Manco L, Miranda J
• Publication Year: 2015
• Journal: Infection Genetics and Evolution
• Link: https://www.sciencedirect.com/science/article/pii/S1567134815001057?via%3Dihub

TPI1 promoter polymorphisms occur in high prevalence in individuals from African origin. Malaria-patients from Angola and Mozambique were screened for the TPI1 gene promoter variants rs1800200A>G, (-5G>A), rs1800201G>A, (-8G>A), rs1800202T>G, (-24T>G), and for the intron 5 polymorphism rs2071069G>A, (2262G>A). -5G>A and -8G>A variants occur in 47% and 53% in Angola and Mozambique, respectively while -24T>G […]
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