Enhanced heterosexual transmission hypothesis for the origin of pandemic HIV-1.
- Autores: Alvarez C, de Sousa JD, Müller V, Vandamme AM
- Journal: Viruses-Basel
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Enhanced+Heterosexual+Transmission+Hypothesis+for+the+Origin+of+Pandemic+HIV-1
HIV-1 M originated from SIVcpz endemic in chimpanzees from southeast Cameroon or neighboring areas, and it started to spread in the early 20th century. Here we examine the factors that may have contributed to simian-to-human transmission, local transmission between humans, and export to a city.