GHTM

Global Health and Tropical Medicine

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Home / Archives for Gaspar J

Pneumocystis jirovecii multilocus genotyping in pooled DNA samples: a new approach for clinical and epidemiological studies.

  • Authors: Antunes F, Esteves F, Gaspar J, Mansinho K, Matos O
  • Journal: Clinical Microbiology and Infection
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Pneumocystis+jirovecii+multilocus+genotyping+in+pooled+DNA+samples%3A+a+new+approach+for+clinical+and+epidemiological+studies.

Specific single-nucleotide polymorphisms (SNPs) are recognized as important DNA sequence variations influencing the pathogenesis of Pneumocystis jirovecii and the clinical outcome of Pneumocystis pneumonia, which is a major worldwide cause of illness among immunocompromised patients
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Population structure of Pneumocystis jirovecii isolated from immunodeficiency virus-positive patients

  • Authors: Antunes F, Esteves F, Gaspar J, Mansinho K, Matos O, Moser I, Tavares A
  • Journal: Infection Genetics and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Population+structure+of+Pneumocystis+jirovecii+isolated+from+immunodeficiency+virus+positive+patients

Pneumocystis jirovecii pneumonia (PcP) is an important opportunistic infection among immunocompromised patients. Genetic characterization of P. jirovecii isolated from HIV-positive patients, based on identification of multiple nucleotide sequences at eight distinct loci, was achieved by using PCR with DNA sequencing and RFLP.
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Identification of relevant single-nucleotide polymorphisms in Pneumocystis jirovecii: relationship with clinical data

  • Authors: Antunes F, Esteves F, Gaspar J, Leite R, Mansinho K, Marques T, Matos O
  • Journal: Clinical Microbiology and Infection
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Identification+of+relevant+Single+Nucleotide+Polymorphisms+in+Pneumocystis+jirovecii%3A+relationship+with+clinical+data

Pneumocystis jirovecii is a poorly understood pathogen that causes opportunistic pneumonia (Pneumocystis pneumonia (PcP)) in patients with AIDS.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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