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Home / Archives for Fernandes L

Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli

  • Autores: Cannalire R, Costa SS, Couto I, Fernandes L, Machado D, Manfroni G, Sabatini S, Tabarrini O, Viveiros M
  • Ano de Publicação: 2017
  • Journal: PeerJ
  • Link: https://peerj.com/articles/3168/%20

Efflux pump inhibitors are of great interest since their use as adjuvants of bacterial chemotherapy can increase the intracellular concentrations of the antibiotics and assist in the battle against the rising of antibiotic-resistant bacteria. In this work, we have described the mode of action of the 2-phenylquinoline efflux inhibitor (4-(2-(piperazin-1-yl)ethoxy)-2-(4-propoxyphenyl) quinolone – PQQ4R), against Escherichia coli, by studding […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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