Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!

Authors: Amaral L, Boeree MJ, Gillespie SH, Udwadia ZF, Van Soolingen D
Journal: International Journal of Antimicrobial Agents
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Thioridazine+cures+extensively+drug-resistant+tuberculosis+(XDR-TB)+and+the+need+for+global+trials+is+now

Thioridazine (TDZ) has been shown to have in vitro activity against multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis, to promote the killing of intracellular MDR and XDR strains and to cure the mouse of antibiotic-susceptible and -resistant pulmonary tuberculosis (TB) infections.
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Activity of the efflux pump inhibitor SILA 421 against drug-resistant tuberculosis

Authors: Amaral L, Boeree MJ, Christensen JB, Hajos G, Kristiansen JE, Molnar J, Riedl Z, Simons SO, Van der Laan T, Van Ingen J, Van Soolingen D, Viveiros M
Journal: International Journal of Antimicrobial Agents
Link: http://www.ncbi.nlm.nih.gov/pubmed/23410790

Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!

Activity of the efflux pump inhibitor SILA 421 against drug-resistant tuberculosis

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