Assessing transmissibility of HIV-1 drug resistance mutations from treated and from drug-naive individuals
- Authors: Abecasis AB, Aerts J, Camacho RJ, Eusebio M, Gomes P, Portuguese HIVRSG, Suchard MA, Theys K, Vandamme AM, Winand R
- Publication Year: 2015
- Journal: AIDS
- Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570689/%20
Surveillance drug resistance mutations (SDRMs) in drug-naive patients are typically used to survey HIV-1-transmitted drug resistance (TDR). We test here how SDRMs in patients failing treatment, the original source of TDR, contribute to assessing TDR, transmissibility and transmission source of SDRMs. This is a retrospective observational study analyzing a Portuguese cohort of HIV-1-infected patients. The […]
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