- Authors: Esteves A, Istrate C, Lima A, Lopes A, Neves E, Nordgren J, Piedade J, Sharma S, Veiga J, Videira e Castro S, Zaky A
- Publication Year: 2015
- Journal: Archives of Virology
- Link: http://www.researchgate.net/publication/266625543_High_rate_of_detection_of_G8P6_rotavirus_in_children_with_acute_gastroenteritis_in_So_Tom_and_Principe
The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in São Tomé and Príncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.
