IT Governance Maturity Patterns in Portuguese Healthcare

The pervasive use of technology in organizations to address the increased services complexity has created a critical dependency on Information Technology (IT) that calls to a specific focus on IT Governance (ITG). However, determining the right ITG mechanisms remains a complex endeavor. This paper uses Design Science Research and proposes an exploratory research by analyzing […]
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Malaria: looking for selection signatures in the human PKLR gene region

Authors: Amorim A, Arez AP, Do Rosário VE, Fernandes N, Gusmão L, Manco L, Miranda J, Pereira R, Rocha AM
Journal: British Journal of Haematology
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Malaria%3A+looking+for+selection+signatures+in+the+human+PKLR+gene+region

The genetic component of susceptibility to malaria is both complex and multigenic and the better-known protective polymorphisms are those involving erythrocyte-specific structural proteins and enzymes. In vivo and in vitro data have suggested that pyruvate kinase deficiency, which causes a nonspherocytic haemolytic anaemia, could be protective against malaria severity in humans, but this hypothesis remains […]
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IT Governance Maturity Patterns in Portuguese Healthcare

Malaria: looking for selection signatures in the human PKLR gene region

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