The contribution of efflux pumps in mycobacterium abscessus complex resistance to clarithromycin
- Authors: Vianna JS, Machado D, Ramis IB, Silva FP, Bierhals DV, Abril MA, von Groll A, Ramos DF, Lourenço MCS, Viveiros M, da Silva PEA
- Publication Year: 2019
- Journal: Antibiotics
- Link: https://www.ncbi.nlm.nih.gov/pubmed/31540480
The basis of drug resistance in Mycobacterium abscessus is still poorly understood. Nevertheless, as seen in other microorganisms, the efflux of antimicrobials may also play a role in M. abscessus drug resistance. Here, we investigated the role of efflux pumps in clarithromycin resistance using nine clinical isolates of M. abscessus complex belonging to the T28 erm(41) sequevar responsible for the inducible resistance […]
Read More