GHTM

Global Health and Tropical Medicine

  • GHTM
    • Vision
    • Mission
    • Governance
    • Scientific Advisory Board
  • News
    • Outreach
    • Events
      • GHTM Sessions
      • Workshops
    • Articles
    • Jobs
  • Research
    • Cross-cutting issues
      • Global Pathogen Dispersion and Population Mobility
      • Drug Discovery and Drug Resistance
      • Diagnostics
      • Public Health Information
      • Fair Research Partnerships
    • Research Groups
      • PPS – Population health, policies and services
      • THOP – TB, HIV and opportunistic diseases and pathogens
      • VBD – Vector borne diseases and pathogens
      • IHC – Individual health care
    • Research in numbers
      • 2022
      • 2021
      • 2020
      • 2019
      • 2018
      • 2017
    • Projects
      • Ongoing Projects
      • Completed Projects
    • Members
      • Population health, policies and services
        • PPS PhD members
        • PPS non PhD members
      • TB, HIV and opportunistic diseases and pathogens
        • THOP PhD members
        • THOP non PhD members
      • Vector-borne diseases and pathogens
        • VBD PhD members
        • VBD non PhD members
      • Individual Health Care
        • IHC PhD members
        • IHC non PhD members
      • Technical / administrative support
  • Publications
    • 2023
    • 2022
  • Education
    • Master Theses
    • PhD Theses
  • Services
  • Reports
    • GHTM Reports
    • Scientific Advisory Board Reports
Home / Publicações / Determinants of HIV-1 Late Presentation in Patients Followed in Europe

Determinants of HIV-1 Late Presentation in Patients Followed in Europe

  • Autores: Miranda MNS, Pingarilho M, Pimentel V, Martins MDRO, Vandamme A-M, Bobkova M, Böhm M, Seguin-Devaux C, Paredes R, Rubio R, Zazzi M, Incardona F, Abecasis A.
  • Ano de Publicação: 2021
  • Journal: Pathogens, 10(7), art 835
  • Link: https://doi.org/10.3390/pathogens10070835

ABSTRACT

To control the Human Immunodeficiency Virus (HIV) pandemic, the World Health Organization (WHO) set the 90-90-90 target to be reached by 2020. One major threat to those goals is late presentation, which is defined as an individual presenting a TCD4+ count lower than 350 cells/mm3 or an AIDS-defining event. The present study aims to identify determinants of late presentation in Europe based on the EuResist database with HIV-1 infected patients followed-up between 1981 and 2019. Our study includes clinical and socio-demographic information from 89851 HIV-1 infected patients. Statistical analysis was performed using RStudio and SPSS and a Bayesian network was constructed with the WEKA software to analyze the association between all variables. Among 89,851 HIV-1 infected patients included in the analysis, the median age was 33 (IQR: 27.0–41.0) years and 74.4% were males. Of those, 28,889 patients (50.4%) were late presenters. Older patients (>56), heterosexuals, patients originated from Africa and patients presenting with log VL >4.1 had a higher probability of being late presenters (p < 0.001). Bayesian networks indicated VL, mode of transmission, age and recentness of infection as variables that were directly associated with LP. This study highlights the major determinants associated with late presentation in Europe. This study helps to direct prevention measures for this population.

 

KEYWORDS

HIV-1 infection; late presentation; Europe.

 

Reference (AMA 11 style)

Miranda MNS, Pingarilho M, Pimentel V, et al. Determinants of HIV-1 Late Presentation in Patients Followed in Europe. Pathogens. 2021; 10(7):835. https://doi.org/10.3390/pathogens10070835

Reference (APA 7 style)

Miranda, M. N. S., Pingarilho, M., Pimentel, V., Martins, M. d. R. O., Vandamme, A-M, Bobkova, M., Böhm, M., Seguin-Devaux, C., Paredes, R., Rubio, R, Zazzi, M, Incardona F, Abecasis A. (2021). Determinants of HIV-1 Late Presentation in Patients Followed in Europe. Pathogens, 10(7), 835. https://doi.org/10.3390/pathogens10070835

 

Journal

Pathogens

 

Share this:

  • Click to share on Facebook (Opens in new window)
  • Click to share on Twitter (Opens in new window)
  • Click to share on LinkedIn (Opens in new window)
  • Click to share on Pinterest (Opens in new window)
  • Click to share on WhatsApp (Opens in new window)
  • Click to print (Opens in new window)

Events

Retention in Care and Virological Failure among Adult HIV-Positive Patients on First-Line Antiretroviral Treatment in Maputo, Mozambique

    “Retention in Care and Virological Failure among Adult HIV-Positive Patients … [Read More...]

European Researchers’ Night 2023: join GHTM researchers to play ‘Hunt for viruses’

  On 29th September, the European Researchers Night reunite Portuguese researchers from all … [Read More...]

Carla Maia awarded by the Journal of Comparative Pathology Education Trust

  Carla Maia, Assistant Researcher and member of VBD-GHTM Research Group, was invited to … [Read More...]

Ciência Viva 2023: “PSI Parasite Scene Investigation – Be a Researcher for a week”

  “PSI Parasite Scene Investigation - Be a Researcher for a week” was the GHTM-IHMT … [Read More...]

Call for PhD Studentships

The Institute of Hygiene and Tropical Medicine (IHMT), Universidade Nova de Lisboa (NOVA), through … [Read More...]

IHMT | GHTM – APPLICATIONS ARE OPEN!

IHMT | GHTM - Applications are open for three research vacancies:   One position - PhD … [Read More...]

About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

Contacts

Rua da Junqueira, 100
1349-008 Lisboa
Portugal
+351 213 652 600
+351 213 632 105

  • Facebook
  • YouTube

Subscribe Newsletter

  • How to get to GHTM/IHMT
  • GHTM Sessions
  • Research Groups
  • Cross-cutting issues
© Copyright 2023 IHMT-UNL Todos os Direitos Reservados.
  • Universidade Nova de Lisboa
  • Fundação para a Ciência e a Tecnologia

    Project UID/Multi/04413/2013