Spectinamides: a challenge, a proof, and a suggestion
- Autores: Pieroni M, Viveiros M
- Ano de Publicação: 2014
- Journal: Trends in Microbiology
- Link: http://www.ncbi.nlm.nih.gov/pubmed/24636244
New drugs and shorter regimens are needed to fight resistant forms of tuberculosis. Screening of chemical libraries for mining hit compounds is the common approach to find new antituberculars. A new medicinal chemistry and biology directed research rational has recently been successfully described by Lee and coworkers in Nature Medicine.