Efflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in Pathogenicity
- Autores: Almeida da Silva PE, Couto I, Machado D, Ramos D, Viveiros M, von Groll A
- Ano de Publicação: 2016
- Journal: Efflux-Mediated Antimicrobial Resistance in Bacteria
- Link: https://link.springer.com/chapter/10.1007/978-3-319-39658-3_21%20
The emergence of multidrug and extensively drug-resistant tuberculosis represents a major threat to the control of the disease. Antimicrobial drug resistance in Mycobacterium tuberculosis is not merely a consequence of the occurrence of gene mutations in the drug targets but a balance between the acquisition of mutations and drug efflux. The low permeability of the […]
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