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Home / Publications / Prevalence of latent tuberculosis and associated factors in patients with chronic kidney disease on hemodialysis

Prevalence of latent tuberculosis and associated factors in patients with chronic kidney disease on hemodialysis

  • Authors: Viviane Ferreira, Cassiane Dezoti da Fonseca, Valdes Roberto Bollela, Elen Almeida Romão, Jose Abrão Cardeal da Costa, Álvaro Francisco Lopes de Sousa, Dulce Aparecida Barbosa
  • Publication Year: 2021
  • Journal: Revista Latino-Americana de Enfermagem, 29, e3442
  • Link: https://doi.org/10.1590/1518-8345.3839.3442

ABSTRACT

‘Objective:’

to identify the prevalence of latent tuberculosis in patients with chronic kidney disease on hemodialysis and associated factors.

‘Method:’

a cross-sectional study conducted with 176 patients with chronic kidney disease on hemodialysis. The tuberculin test was performed with the standardized antigen, distributed by the Brazilian Ministry of Health, and the reading occurred after 72 to 96 hours of the application. An association test (Chi-square, Fisher’s exact), prevalence ratio, and multivariate regression tests were performed.

‘Results:’

the prevalence of latent tuberculosis diagnosed through Tuberculosis Skin Test was 8.5% (15/176). The “has/has had diabetes” (aOR: 0.117; 95%CI: 0.015-0.92) and “having regular garbage collection (aOR: 0.076; 95%CI: 0.008-0.702) factors were associated with a lower probability of having a Positive skin test.

‘Conclusion:’

the low prevalence of latent tuberculosis identified and the factors associated with it reinforce the need for screening for latent tuberculosis infection for diabetics combined with an analysis of previous risk factors and comorbidities.

KEYWORDS

Chronic Kidney Diseases; Diabetes Mellitus; Hemodialysis; Tuberculin Test; Renal Replacement Therapy; Latent Tuberculosis.

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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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