Events 2022 – External02 » 1st Conference FMUL/FMUC: Infectious Diseases and Vaccines
- From: 09/04/2022
- To: 09/04/2022
- Location: https://janssenpt.webex.com/join/fmul
Global Health and Tropical Medicine
The increasing demand and use of high-quality samples and data place biobanks at the centre of basic and translational research. This seminar will address the importance of pre-analytical quality for sample diagnosis validation in order to help researchers meet the highest quality standards for their research.
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In May 2020, the Cascais City Council established a partnership with GHTM to conduct a community-level seroprevalence survey, which included blood serology testing for SARS-CoV-2 antibodies together with socio-demographic and clinical questions. The study’s 1st phase was between May and September 2020 and had 12,032 respondents – 5.62% of Cascais population. The reactive tests’ %s were, respectively: 1.3 overall, 1.16 females and 1.56 males; having the 20-39 age group the highest prevalence (2%).
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Adductomics is a powerful tool to link exposure with the occurrence of diseases, constituting an opportunity for the identification of risk factors, molecular mechanisms of adverse outcomes and biomarkers for early disease diagnosis. Additionally, adductomics can guide regulatory and preventive actions, thereby leading to the minimization of exposure-related health adverse outcomes.
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Traditional light-microscopy of stained smears may be replaced by fluorescent stains.
The auramine-O Acid-Fast-Stain (AFS) does not stain the cell-wall (mycolic acids), but is a classical DNA/RNA stain, whereby the cell wall only protects the microorganisms from decolorization by the acid. Confirmation of this new concept opens up the possibility to use this stain in different contexts: a) Auramine-O AFS allows the simple detection of Schistosome eggs; b) Auramine-O AFS allows detection of mycobacteria in histological samples; c) newer nucleic acid-stains may increase (broaden) the application of this stain.
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