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Global Health and Tropical Medicine

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Epidemiological and genetic studies suggest a common Leishmania infantum transmission cycle in wildlife, dogs and humans associated to vector abundance in Southeast Spain

Leishmania infantum infection was investigated in 202 wild carnivores, rodents and lagomorphs in Southeast Spain using a real-time PCR (rtPCR) in skin and organ samples, mostly spleen. Lesions compatible with leishmaniosis were not observed in any of the animals. Prevalence defined as the percentage of rtPCR-positive animals was 32% overall, and 45% in foxes (n = 69), 30% […]
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Parasite biology: The reservoir hosts

Leishmaniases are worldwide vector-borne diseases with diverse clinical manifestations caused by protozoa belonging to genus Leishmania. About 20 named Leishmania species are pathogenic for humans and are annually responsible for 0.7–1.2 million cases of cutaneous and 0.2–0.4 million cases of visceral forms of the disease. According to the transmission cycle involving animals or humans, leishmaniasis can be […]
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Synopsys of the 3rd National Congress of Tropical Medicine and 1st Lusophone Congress of Vector-Borne Diseases

Currently, Tropical Medicine emerged as both an important medical specialty and scientific discipline assuming a preponderant global dimension. Until a few years ago, several tropical pathologies, which were exclusively associated with tropical regions, have been gradually expanding to other geographic areas previously considered free of these infections. Vector-borne diseases are included among this group of […]
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Report of in vitro antileishmanial properties of Iberian macroalgae

ere is reported the anti Leishmania infantum activity of 48 hexane, CH2Cl2 and MeOH extracts from 16 macroalgae collected on the Iberian Coast. Seven hexane and CH2Cl2 Cystoseira baccata, Cystoseira barbata, Cystoseira tamariscifolia, Cystoseira usneoides, Dictyota spiralis and Plocamium cartilagineum extracts were active towards promastigotes (IC50 29.8–101.8 μg/mL) inducing strong morphological alterations in the parasites. Hexane extracts of C. […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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