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Home / Publications / Human seroprevalence of Toscana virus and Sicilian phlebovirus in the southwest of Portugal

Human seroprevalence of Toscana virus and Sicilian phlebovirus in the southwest of Portugal

  • Authors: Carla Maia, Nazli Ayhan, José Manuel Cristóvão, André Pereira, Remi Charrel
  • Publication Year: 2021
  • Journal: European Journal of Clinical Microbiology and Infectious Diseases, 41(1), 137-141
  • Link: https://doi.org/10.1007/s10096-021-04332-0

ABSTRACT

Toscana virus (TOSV) is emergent in the Mediterranean region and responsible for outbreaks of encephalitis or meningoencephalitis. Sicilian phlebovirus (SFSV) cause epidemics of febrile illness during the summer. The aim of this study was to evaluate the presence of antibodies against TOSV and SFSV in humans in the southwest of Portugal. Neutralizing antibodies to TOSV and SFSV were respectively detected in 5.3% and 4.3% out of 400 human sera tested highlighting the need to increase public health awareness regarding phleboviruses and to include them in the differential diagnosis in patients presenting with fever of short duration and neurological manifestations.

 

KEYWORDS

Toscana virus; Mediterranean region; encephalitis; meningoencephalitis; Sicilian phlebovirus.

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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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