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Home / Articles / GHTM Sessions 2021 – CCID05 » Molecular tools for mapping and monitoring schistosomiasis in endemic settings

GHTM Sessions 2021 – CCID05 » Molecular tools for mapping and monitoring schistosomiasis in endemic settings

May 17, 2021

O Instituto de Higiene e Medicina Tropical apresenta o ciclo de palestras GHTM SESSIONS, do Centro de Investigação Saúde Global e Medicina Tropical (Global Health and Tropical Medicine – GHTM), com o qual partilha o trabalho dos seus investigadores.
Este ciclo é dedicado às inovações científicas, aqui produzidas, na área do diagnóstico de doenças infecciosas.

As GHTM SESSIONS seguirão o seguinte programa.

As palestras estão abertas a todos e decorrerão em português, através do acesso Zoom:
https://videoconf-colibri.zoom.us/j/88939262378?pwd=S0pIT002NkpkdkNDay95UUcwOVk0QT09

ID: 889 3926 2378
Password: 787895

A palestra de 19 de maio de 2021, às 11h00, a cargo do investigador Dr. Pedro Ferreira – GHTM / Instituto de Higiene e Medicina Tropical – Universidade Nova, VBD, terá como tema:

Ferramentas moleculares para mapear e monitorizar a schistosomose numa área endémica

A avaliação dos programas de controlo da schistosomose, uma doença, transmitida por caracóis de água doce, causada pelo Schistosoma spp, requer técnicas de diagnóstico precisas para avaliar o estado da infecção, quando a baixa prevalência é alcançada em áreas endémicas sob administração de fármacos em massa (AFM). As técnicas parasitológicas atuais, recomendadas pela OMS, mostram sensibilidade subótima e subestimação da morbilidade da schistosomose, particularmente em áreas de baixa transmissão. Uma abordagem alternativa baseada em ferramentas moleculares pode superar essa limitação, melhorando o desempenho do diagnóstico na monitorização dos impactos da AFM, bem como ser usada como padrão na validação de novos testes, incluindo o teste sorológico imunocromatográfico POC-CCA a ser aplicado em localizações com poucos recursos.

Esperamos a vossa presença!

Molecular tools for mapping and monitoring schistosomiasis in endemic settings

Evaluation of schistosomiasis control programs, a snail-borne disease caused by Schistosoma spp, requires accurate diagnostic techniques to assess the infection status when low prevalence is achieved in endemic areas under mass drug administration (MDA). The current parasitological techniques recommended by WHO show suboptimal sensitivity and underestimation of schistosomiasis morbidity particularly in low transmission areas. Alternative approach based on molecular tools may overcame this limitation, improving diagnostic performance for monitoring MDA impacts as well as be used as gold standard for validation of new developed tests including the immunocromatographic POC-CCA serologic test to be applied in low-resourced field settings.

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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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