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Home / Eventos / GHTM Sessions | Biotechnology approach to develop green bio-pesticides

GHTM Sessions | Biotechnology approach to develop green bio-pesticides

GHTM Sessions

  • De: 14/01/2020
  • Até: 14/01/2020
  • Localização: Sala Professor Fraga de Azevedo | 11h00

Paulo Eduardo Martins Ribolla I Universidade Estadual Paulista (UN ESP)

Despite the RNAi consolidation as viable alternative in insect management worldwide, this biopesticide methodology remains unexplored in Brazilian conditions. Therefore, this project aims to develop new targets for the use of shRNA as biopesticides against tropical diseases vectors as Anopheles, Aedes and Lutzomyia. The project is divided into four objectives [OJ. 01: To identify and validate potential genes for the development of RNAi in different mosquito borne diseases by shotgun sequencing. 02: Soaking assays to test the candidate shRNA targets against the target insects. 03: Optimization of successful molecules by Saccharomyces cerevisiae expression and further evaluated using feeding assays to verify the viability of in vivo supply. 04: Evaluation of bioinsecticide efficiency by genetic tools analysis of locally interventions.

 

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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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