Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives

• Authors: Böttger E, Cambau E, Köser CU, Miotto P, Schön T, Viveiros M
• Publication Year: 2017
• Journal: Clinical Microbiology and Infection
• Link: http://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(16)30511-0/fulltext

Drug-resistance testing, or antimicrobial susceptibility testing (AST), is mandatory for Mycobacterium tuberculosis in cases of failure on standard therapy. We reviewed the different methods and techniques of phenotypic and genotypic approaches. Although multiresistant and extensively drug-resistant (MDR/XDR) tuberculosis is present worldwide, AST for M. tuberculosis (AST-MTB) is still mainly performed according to the resources available rather […]
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