Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection
- Authors: Appelberg R, Cortes S, Cruz T, Fernandes A, Gomes MS, Marques F, Marques JM, Neves JV, Rocha E, Rodrigues P, Silva T, Tomás AM, Vale-Costa S
- Publication Year: 2015
- Journal: Parasites & Vectors
- Link: https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-015-1259-6%20
Visceral leishmaniasis is a severe and potentially fatal disease caused by protozoa of the genus Leishmania, transmitted by phlebotomine sandflies. In Europe and the Mediterranean region, L. infantum is the commonest agent of visceral leishmaniasis, causing a wide spectrum of clinical manifestations, including asymptomatic carriage, cutaneous lesions and severe visceral disease. Visceral leishmaniasis is more […]
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