GHTM

Global Health and Tropical Medicine

Home / Profiles / Ana Paula Arez

Ana Paula Arez

Principal Researcher

GHTM Group: VBD PhD members, Vector-borne diseases and pathogens

ResearchTop 5 Publications

 Main areas of research:

1) Mechanisms of host susceptibility to malaria disease/infection especially related to erythrocyte disorders;

2) Characterization and transmission dynamics of parasite populations;

3) Development of new methods of malaria diagnosis.

  1. Guerra M, Neres R, Salgueiro P, Mendes C, Ndong-Mabale N, Berzosa P, de Sousa B, Arez AP 2017. Plasmodium falciparum Genetic Diversity in Continental Equatorial Guinea before and after Introduction of Artemisinin-Based Combination Therapy. Antimicrobial Agents and Chemotherapy. 61: e02556-15. doi: 10.1128/AAC.02556-15
  2.  Guerra M, Machado P, Manco L, Fernandes N, Miranda J, Arez AP 2015. Triosephosphate isomerase gene promoter variation: -5G/A and -8G/A polymorphisms in clinical malaria groups in two African populations. Infection. Genetics and Evolution, 32: 271–279. DOI: 10.1016/j.meegid.2015.03.020
  3. Mendes C, Salgueiro P, Gonzalez V, Berzosa P, Benito A, do Rosário V.E., Sousa B., Cano J., Arez AP 2013. Genetic diversity and signatures of selection of drug resistance in Plasmodium populations from both human and mosquito hosts in continental Equatorial Guinea.Malaria Journal, 12: 114. DOI: 10.1186/1475-2875-12-114
  4.  Machado P, Manco L, Gomes C, Mendes C, Fernandes N, Salomé G, Sitoe L, Chibute S, Langa J, Ribeiro L, Miranda J, Cano J, Pinto J, Amorim A, do Rosário VE, Arez AP 2012. Pyruvate kinase deficiency in sub-Saharan Africa: identification of a highly frequent missense mutation (G829A;Glu277Lys) and association with malaria. PLoS ONE, 7: e47071. DOI: 10.1371/journal.pone.0047071
  5. Mendes C, Dias F, Figueiredo J, Gonzalez VM, Cano J, de Sousa B, do Rosário VE, Benito A, Berzosa P, Arez AP 2011. Duffy negative antigen is no longer a barrier to Plasmodium vivax – molecular evidences from the African West Coast (Angola and Equatorial Guinea).PLoS Neglected Tropical Diseases, 5: e1192. DOI: 10.1371/journal.pntd.0001192

About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

Contacts

Rua da Junqueira, 100
1349-008 Lisboa
Portugal
+351 213 652 600
+351 213 632 105

Subscribe Newsletter