Date: 24 September 2025
Time: 13:30-14:30
Location: ZOOM
This presentation will highlight key immune mechanisms in an experimental model of Leishmania amazonensis infection. We will focus on both regulatory and inflammatory processes that may contribute to immunopathogenesis, such as IL-10 production by B cells, T-cell exhaustion, and IL-17–producing γδ T cells. In addition, we will discuss mechanisms associated with vaccination strategies, cell-based therapies, and immunotherapy approaches.
About Herbert Guedes
Herbert Leonel de Matos Guedes is an Associate Professor at the Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro (IMPG/UFRJ), and a Public Health Researcher at the Oswaldo Cruz Institute, Oswaldo Cruz Foundation (IOC/FIOCRUZ). He is a CNPq Productivity Fellow (Level 1D) and a Cientista do Nosso Estado Fellow (FAPERJ).
He earned his degree in Pharmacy at UFRJ (2000–2003), followed by a Master’s (2003–2005) and PhD (2005–2009) in Biophysics at the Carlos Chagas Filho Institute of Biophysics, with part of his doctoral training conducted at the University of Glasgow (Scotland, UK) and the Albert Einstein College of Medicine (New York, USA). He completed postdoctoral training at the Carlos Chagas Filho Institute of Biophysics and at the University of Texas Medical Branch in Galveston, USA.
Professor Guedes leads the research group on Immunology and Vaccinology, serves as Head of the Laboratory of Immunobiotechnology (IMPG/UFRJ), and Head of the Laboratory of Clinical Immunology at IOC/FIOCRUZ.
If you are a GHTM member, you will receive the details of the session by e-mail. If you are not a GHTM member and would like to join the session, please contact us at ghtm-info@ihmt.unl.pt.