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Home / Archives for Donnelly MJ

Geographic population structure of the African malaria vector Anopheles gambiae suggests a role for the forest-savannah biome transition as a barrier to gene flow

  • Authors: Caccone A, Charlwood JD, Della Torre A, Donnelly MJ, Egyir-Yawson A, Elissa N, Gomes B, Moreno M, Santolamazza F, Simard F, Vicente JL, Weetman D
  • Journal: Evolutionary Applications
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24062800

The primary Afrotropical malaria mosquito vector Anopheles gambiae sensu stricto has a complex population structure. In west Africa, this species is split into two molecular forms and displays local and regional variation in chromosomal arrangements and behaviors.
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Hybridization and population structure of the Culex pipiens complex in the islands of Macaronesia.

  • Authors: Almeida AP, Alves J, Donnelly MJ, Gomes B, Santa-Ana M, Silva TL, Sousa CA, Vieira I
  • Journal: Ecology and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Hybridization+and+population+structure+of+the+Culex+pipiens+complex+in+the+islands+of+Macaronesia.

The Culex pipiens complex includes two widespread mosquito vector species, Cx. pipiens and Cx. quinquefasciatus. The distribution of these species varies in latitude, with the former being present in temperate regions and the latter in tropical and subtropical regions.
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Gene flow-dependent genomic divergence between Anopheles gambiae M and S forms.

  • Authors: Donnelly MJ, Steen K, Weetman D, Wilding CS, Pinto J
  • Journal: Molecular Biology and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Gene+flow-dependent+genomic+divergence+between+Anopheles+gambiae+M+and+S+forms

Anopheles gambiae sensu stricto exists as two often-sympatric races termed the M and S molecular forms, characterized by fixed differences at an X-linked marker. Extreme divergence between M and S forms at pericentromeric “genomic islands” suggested that selection on variants therein could be driving interform divergence in the presence of ongoing gene flow, but recent work has detected much more widespread genomic differentiation.
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Feeding patterns of molestus and pipiens forms of Culex pipiens (Diptera: Culicidae) in a region of high hybridization

  • Authors: Almeida AP, Arez E, Calderón I, Donnelly MJ, Gomes B, Pinho L, Pinto J, Sousa CA, Vicente JL
  • Journal: Parasites & Vectors
  • Link: http://www.parasitesandvectors.com/content/6/1/93

Two biological forms of the mosquito Culex pipiens s.s., denoted pipiens and molestus, display behavioural differences that may affect their role as vectors of arboviruses. In this study, the feeding patterns of molestus and pipiens forms were investigated in Comporta (Portugal), where high levels of inter-form admixture have been recorded.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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