Active antimicrobial efflux in Staphylococcus epidermidis: building up of resistance to fluoroquinolones and biocides in a major opportunistic pathogen
- Authors: Costa SS, Couto I, Pomba C, Viveiros M
- Publication Year: 2017
- Journal: Journal of Antimicrobial Chemotherapy
- Link: https://academic.oup.com/jac/article/73/2/320/4604698
To analyse the efflux-mediated response of Staphylococcus epidermidis to ethidium bromide (EtBr), a substrate of multidrug efflux pumps (EPs). The susceptible reference strain S. epidermidis ATCC 12228 was exposed to a step-wise adaptation to EtBr. The resulting EtBr-adapted strains were characterized regarding their antibiotic and biocide susceptibility by MIC determination and evaluation of efflux activity […]
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