Miguel Viveiros

His main areas of interest are centred in the support of the mission and institutional strategy of teaching and capacity building for the Community of Portuguese Language Countries (CPLP) in Biomedical Sciences, International Health and Tropical Medicine. Scientific activity devoted to the early diagnosis of active or latent tuberculosis (TB) infections as well as the development of new diagnostic and therapeutic approaches to deal with MDRTB and with other drug resistant bacterial infections. Research mainly focused on tuberculosis and antibiotic resistant infections in support for alternative therapies of incurable diseases such as multidrug resistant tuberculosis and methicillin-vancomycin resistant staphylococcal infections using non-antibiotic adjuvants of the chemotherapy, as well as the early diagnosis of tuberculosis in low-resource countries by new nanotechnology based technologies. Also interested in molecular biology of mycobacteria and immunology of TB. As Director of the TB Laboratory of the IHMT (since 2001) has contributed to the resolution of the pulmonary TB problem of Lisbon by the generation of complete reports within a period of 15 to 20 days for 10 Hospitals of the TB Task Force of Lisbon. He has led various research projects in those areas, supervised several postgraduate degrees. Founding member and Treasurer (until 2017), currently management committee member of the Study Group for Mycobacterial Infections (ESGMYC) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) (https://www.escmid.org/index.php?id=897 ). Elected Vice-chair of the Gordon Research Conference – Multi-Drug Efflux Systems – 2017-2019 – https://www.grc.org/multi-drug-efflux-systems-conference/2019/). Author/co-author of over 150 scientific papers in peer review national and international journals in mycobacteriology, bacteriology, resistance to antibiotics, microbial genetics, molecular epidemiology and immunology and 20 book chapters, with a Scopus H-index of 38 / Google Scholar H-Index of 45.

URL : http://www.scopus.com/authid/detail.url?authorId=7003949212

URL : http://scholar.google.pt/citations?user=o39byr4AAAAJ&hl=en

URL : http://orcid.org/0000-0001-9676-6251

1. Coll F, Phelan J, Hill-Cawthorne GA, Nair MB, Mallard K, Ali S, Abdallah AM, Alghamdi S, Alsomali M, Ahmed AO, Portelli S, Oppong Y, Alves A, Bessa TB, Campino S, Caws M, Chatterjee A, Crampin AC, Dheda K, Furnham N, Glynn JR, Grandjean L, Minh Ha D, Hasan R, Hasan Z, Hibberd ML, Joloba M, Jones-López EC, Matsumoto T, Miranda A, Moore DJ, Mocillo N, Panaiotov S, Parkhill J, Penha C, Perdigão J, Portugal I, Rchiad Z, Robledo J, Sheen P, Shesha NT, Sirgel FA, Sola C, Oliveira Sousa E, Streicher EM, Helden PV, Viveiros M, Warren RM, McNerney R, Pain A, Clark TG.
   Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nat Genet. 2018 Feb;50(2):307-316. doi: 10.1038/s41588-017-0029-0. Epub 2018 Jan 22. https://www.nature.com/articles/s41588-017-0029-0
2. Perdigão J, Silva C, Diniz J, Pereira C, Machado D, Ramos J, Silva H, Abilleira F, Brum C, Reis AJ, Macedo M, Scaini JL, Silva AB, Esteves L, Macedo R, Maltez F, Clemente S, Coelho E, Viegas S, Rabna P, Rodrigues A, Taveira N, Jordao L, Kritski A, E Silva JL, Mokrousov I, Couvin D, Rastogi N, Couto I, Pain A, McNerney R, Clark TG, von Groll A, Dalla-Costa ER, Rossetti ML, da Silva PEA, Viveiros M, Portugal I. Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries. Infect Genet Evol. 2018 Mar 17. pii: S1567-1348(18)30102-3. doi: 10.1016/j.meegid.2018.03.011. [Epub ahead of print] https://www.sciencedirect.com/science/article/pii/S1567134818301023?via%3Dihub
3. Machado D, Coelho TS, Perdigão J, Pereira C, Couto I, Portugal I, Maschmann RA, Ramos DF, von Groll A, Rossetti MLR, Silva PA, Viveiros M. Interplay between  Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis. Front Microbiol. 2017 Apr 27;8:711. doi: 10.3389/fmicb.2017.00711. http://journal.frontiersin.org/article/10.3389/fmicb.2017.00711/full
4. Schön T, Miotto P, Köser CU, Viveiros M, Böttger E, Cambau E. Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives. Clin Microbiol Infect. 2017 Mar;23(3):154-160. doi: 10.1016/j.cmi.2016.10.022. http://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(16)30511-0/pdf
5. Machado D, Pires D, Perdigão J, Couto I, Portugal I, Martins M, Amaral L, Anes E, Viveiros M. Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis. PLoS One. 2016 Feb 26;11(2):e0149326. doi: 10.1371/journal.pone.0149326. eCollection 2016. PubMed PMID: 26919135; PubMed Central PMCID: PMC4769142. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149326